1-(3',4'-Methylenedioxyphenyl)-2-pyrrolidino-1-pentanone hydrochloride - Names and Identifiers
1-(3',4'-Methylenedioxyphenyl)-2-pyrrolidino-1-pentanone hydrochloride - Physico-chemical Properties
| Molecular Formula | C16H22ClNO3
|
| Molar Mass | 311.804 |
| Boling Point | 442.7°C at 760 mmHg |
| Flash Point | 221.6°C |
| Vapor Presure | 3.04E-08mmHg at 25°C |
1-(3',4'-Methylenedioxyphenyl)-2-pyrrolidino-1-pentanone hydrochloride - Introduction
1-(3 ',4'-Methylenedioxyphenyl)-2-pyrrolidino-1-pentanone hydrochloride is a compound with the formula C14H18NO3 · HCl. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in water and ethanol
-Used as: This compound is a phenyl ethyl ketone compound and has a central nervous stimulation effect. It is sometimes used as a stimulant and mood stabilizer. It also has some sedative and hypnotic effects.
Method:
The preparation of 1-(3 ',4'-Methylenedioxyphenyl)-2-pyrrolidino-1-pentanone hydrochloride is usually completed by the following steps:
1. First, 3,4-methylenedioxyphenylacetic acid and anhydrous aluminum chloride are heated to react in sulfuric acid.
2. Next, the obtained intermediate is reacted with bromobutane in alcohol to form the corresponding bromine-substituted compound.
3. Finally, the bromine substituent is reacted with pyrrolidone in the presence of sodium borohydride and sodium hydroxide to form 1-(3 ',4'-Methylenedioxyphenyl)-2-pyrrolidino-1-pentanone hydrochloride.
Safety Information:
This compound should be handled and used with caution because it has certain toxicity. Appropriate laboratory safety measures, such as wearing gloves, laboratory coats and goggles, should be taken during handling and storage. Inhalation of its dust and contact with skin should be avoided. In addition, local safety regulations must be observed and used in a suitable environment. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15